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A direct and sensitive method for the determination of salicylamide in micro plasma samples by high performance liquid chromatography using fluorescence detection


A direct and sensitive method for the determination of salicylamide in micro plasma samples by high performance liquid chromatography using fluorescence detection



Analytical Letters 14(8): 577-582



ISSN/ISBN: 0003-2719

A quantitative analysis of salicylamide in microplasma volumes by high-performance liquid chromatography [HPLC] using fluorescence detection is reported. The procedure is extremely simple and rapid, involving the direct introduction of the human plasma sample on the HPLC column. The assay procedure is linear over the concentration range studied, 0-100 ng/ml with the linear regression correlation coefficient, r = 0.998. This assay procedure enables the detection of salicylamide as low as 5.0 ng/ml in plasma, using sample volume of 100 .mu.l.

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Accession: 004571165

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