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A finding of coronavirus particles in feces of patients with diarrhea

A finding of coronavirus particles in feces of patients with diarrhea

Chinese Journal of Epidemiology 8(1): 25-27

An outbreak of epidemic diarrhea occurred during March-April period in 1984 at a village of Donfong County of Jilin Province [China]. 10 fecal samples as well as 10 paired sera from clinical cases were collected and other 20 fecal samples as well as 20 serum samples from healthy individuals in the village were used as controls. Coronavirus-like particles were seen in all the fecal samples collected from acute cases using electron microscopy but not in control samples. The coronavirus-like particles were aggregated by convalescent-phase sera in immune electron microscopy. The micro complement fixation test using specific extracted antigen was carried out.9 out of 10 paired sera from the patients showed 4-fold or more increase titre while sera from healthy controls were negative.

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Accession: 004573887

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