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A new model of dna and histone organization in chromatin explanation of conformational transitions in chromatin structure and their dissociation



A new model of dna and histone organization in chromatin explanation of conformational transitions in chromatin structure and their dissociation



Studia Biophysica 75(2): 107-130



A new model describing the arrangement of the apolar histone heads and the terminal basic histone regions in the core particle is proposed. On the basis of the core particle model, a novel principle for the construction of the chromatin thread is suggested and the salt-induced dynamics of chromatin structure and dissociation are explained. This is accomplished by a consideration of the balance of hydrophobic and electrostatic interactions which determine the dynamics of chromatin structure.

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Accession: 004597435

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