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Allelic Variants at the Xanthine Dehydrogenase Locus Affecting Enzyme Activity in DROSOPHILA PSEUDOOBSCURA

Prakash, S.

Genetics 87(1): 159-168

1977


ISSN/ISBN: 0016-6731
PMID: 17248755
Accession: 004697875

Quantitative studies of enzyme activity on gels show about four-fold differences in enzyme activity of different xanthine dehydrogenase (XDH ) alleles. At least three different activity classes could be distinguished among the 23 strains isogenic for the XDH locus. No association of high activity with the high frequency electromorph was observed; instead, the low frequency electromorphs had 0.5 to 2 times the activity of the high frequency electromorph. The frequency of low activity, high activity and intermediate activity XDH alleles among these 23 lines is 0.13, 0.09, and 0.78, respectively.

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