EurekaMag
+ Translate
+ Most Popular
Advantages and disadvantages of bordeaux mixture and of lime-sulphur used on apples in the growing season
Observations on the Umaria marine bed
10 years of hearing conservation in the Royal Air Force
Chocolate crumb - dairy ingredient for milk chocolate
Effect of daily gelatin ingestion on human scalp hair
Comparison of rice bran and maize bran as feeds for growing and fattening pigs
The composition of pampas-grass (Cortaderia argentea.)
The Accraian Series:
The mechanism of the Liebermann-Burchard reaction of sterols and triterpenes and their esters
Cerebrovascular Doppler ultrasound studies (cv-Doppler)
Toria: PT-303 - first national variety
Hair growth promoting activity of tridax procumbens
Productivity of Pekin x Khaki Campbell ducks
A stable cytosolic expression of VH antibody fragment directed against PVY NIa protein in transgenic potato plant confers partial protection against the virus
Solar treatment of wheat loose smut
Swimmers itch in the Lake of Garda
Bactofugation and the Bactotherm process
The effects of prefrontal lobotomy on aggressive behavior in dogs
Visual rating scales for screening whorl-stage corn for resistance to fall armyworm
Breakdown of seamounts at the trench axis, viewed from gravity anomaly
Kooken; pennsylvania's toughest cave
Recovery of new dinosaur and other fossils from the Early Cretaceous Arundel Clay facies (Potomac Group) of central Maryland, U.S.A
Zubor horny (Bison bonasus) v prirodnych podmienkach Slovensku
The extended Widal test in the diagnosis of fevers due to Salmonella infection
Hair of the american mastodon indicates an adaptation to a semi aquatic habitat

Alpha 1 antitrypsin pi types in asian pacific and aboriginal australian populations


Alpha 1 antitrypsin pi types in asian pacific and aboriginal australian populations



Disease Markers 1(1): 33-42



ISSN/ISBN: 0278-0240

Isoelectric focusing in thin-layer polyacrylamide gels has been used to examine the phenotypes of alpha-1-antitrypsin (PI) in 5444 individuals from Asian, Pacific and Australian Aboriginal populations. A marked variation was observed in the distribution of PI M subtypes in different ethnic groups. The highest frequencies of PI*M2 alleles were observed in the Papua New Guinea Highlands (67 percent) and Australian Aboriginal populations (62 percent). High frequencies of P1*M2 alleles were found also in lowland Papua New Guineans, most Indonesian populations as well as Fiji and Nauru and were significantly lower in other Asian and Pacific Island populations (12-25 percent). Indian samples are characterized by having high frequencies (up to 20 percent) of the PI*M3 allele, whereas other populations showed low frequencies of this allele varying from 1 to 11 percent. No examples of the deficient Z phenotypes were observed. However, a new non-deficient allele. PIIndonesia, was detected at polymorphic frequencies in three Indonesian populations. The PI*S allele was present sporadically in Indonesia, Pacific and central Australian Aboriginal populations.

Please choose payment method:






(PDF emailed within 1 workday: $29.90)

Accession: 004700234

Download citation: RISBibTeXText

Related references

Distribution of transferrin (Tf) subtypes in Asian, Pacific and Australian Aboriginal populations: evidence for the existence of a new subtype TfC6. Human Heredity 33(4): 237-243, 1983

The evolution and diversity of TNF block haplotypes in European, Asian and Australian Aboriginal populations. Genes and Immunity 10(7): 607-615, 2009

Dental arch form in three Pacific populations: a comparison with Japanese and Australian aboriginal samples. Journal of Nihon University School of Dentistry 39(4): 196-201, 1997

Dental arch form in three Pacific populations: a comparison with Japanese and Australian Aboriginal samples. The Journal of Nihon University School of Dentistry 39(4): 196-201, 1997

Alpha-1-antitrypsin (Pi) types in Korean and Chinese populations. Human Genetics 57(3): 327-328, 1981

Opening remark: Workshop on the Epidemiological Survey of Chronic Obstructive Lung Diseases and Alpha-1-antitrypsin Deficiency in the Asian-Pacific Region. Respirology 6(3): 269-269, 2001

Gender variations in waist circumference levels between Aboriginal and non-Aboriginal Australian populations: a systematic review. Obesity Research and Clinical Practice 8(6): E513-E524, 2014

Alpha 1-antitrypsin deficiency caused by the alpha 1-antitrypsin Nullmattawa gene. An insertion mutation rendering the alpha 1-antitrypsin gene incapable of producing alpha 1-antitrypsin. Journal of Clinical Investigation 83(4): 1144-1152, 1989

Differences in cancer incidence by age at diagnosis between Aboriginal and non-Aboriginal people for cancer types included in Australian national screening programs. Cancer Epidemiology 60: 102-105, 2019

Biochemical intermediates in alpha 1-antitrypsin deficiency: residual family resemblance for total alpha 1-antitrypsin, oxidized alpha 1-antitrypsin, and immunoglobulin E after adjustment for the effect of the Pi locus. Genetic Epidemiology 7(2): 137-149, 1990

Recombinant dna produced valine 358 alpha 1 antitrypsin more effectively resists oxidative inactivation by alveolar macrophages of cigarette smokers than plasma derived m 1m 1 alpha 1 antitrypsin or methionine 358 alpha 1 antitrypsin. American Review of Respiratory Disease 133(4 Suppl.): A218, 1986

Alpha 1-antitrypsin Null(isola di procida): an alpha 1-antitrypsin deficiency allele caused by deletion of all alpha 1-antitrypsin coding exons. American Journal of Human Genetics 47(3): 403-413, 1990

Comparison of alpha-1-antitrypsin levels and antineutrophil elastase capacity of blood and lung in a patient with the alpha-1-antitrypsin phenotype null-null before and during alpha-1-antitrypsin augmentation therapy. American Review of Respiratory Disease 135(3): 539-543, 1987

Pulmonary branch national heart lung and blood institute bethesda maryland usa alpha 1 antitrypsin deficiency replacement study chronic augmentation of the antineutrophil elastase capacity of the lower respiratory tract of alpha 1 antitrypsin deficient individuals with weekly infusions of alpha 1 antitrypsin. American Review of Respiratory Disease 133(4 Suppl.): A103, 1986

Supplement: Some Environmental and Cultural Factors Influencing the Structuring of Australian Aboriginal Populations || Some Environmental and Cultural Factors Influencing the Structuring of Australian Aboriginal Populations. American Naturalist 87(834): 171-207, 1953