+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Amino terminal amino acid sequence of the major structural poly peptides of avian retroviruses sequence homology between reticuloendotheliosis virus p 30 and p 30 of mammalian retroviruses



Amino terminal amino acid sequence of the major structural poly peptides of avian retroviruses sequence homology between reticuloendotheliosis virus p 30 and p 30 of mammalian retroviruses



Proceedings of the National Academy of Sciences of the United States of America 75(6): 2708-2712



The major structural polypeptides, p30 of reticuloendotheliosis virus (REV) (strain T) and p27 of avian sarcoma virus B77, were compared with regard to amino acid composition, NH2-terminal amino acid sequence and immunonological crossreaction. The amino acid composition of the 2 polypeptides is distinct, and a comparison of the first 30 NH2-terminal amino acids of REV p30 with that of the first 25 of B77 p27 yields only 3 homologous residues. In competition radioimmunoassays the polypeptides show no crossreactivity. A comparison of the amino acid composition and NH2-terminal amino acid sequence of REV p30 with those reported for several mammalian retrovirus p30 shows remarkable similarities. Both REV and mammalian p30 contain a large number of polar residues in their amino acid composition and show approximately 40% homology in the first 30 NH2-terminal amino acids. No crossreactivity could be observed in competition radioimmunoassays between Rauscher murine leukemia virus p30 and that of REV. The observations reported here suggest a close evolutionary relationship between REV and the mammalian retroviruses.

Please choose payment method:






(PDF emailed within 1 workday: $29.90)

Accession: 004710801

Download citation: RISBibTeXText

PMID: 208072


Related references

Amino-terminal sequence of baboon type C virus p30. Virology 64(2): 581-583, 1975

Amino acid sequence homology in 30s ribosomal protein s 19 from bacillus stearothermophilus and escherichia coli. Biochimica et Biophysica Acta 427(1): 371-374, 1976

The amino acid sequence of clostridium pasteurianum iron protein a component of nitrogenase part 2 cyanogen bromide peptides. Journal of Biological Chemistry 252(20): 7089-7092, 1977

A multicomponent mandibular gland secretion in the ponerine ant Bothroponera soror (Emery). Journal of Insect Physiology 268: 551-555, 1980

Amino-acids of Amoebotaenia cuneata (Cestoda: Dilepidoidea Wardle McLeod & Radinovsky, 1974). Journal of Helminthology 57(1): 9-10, 1983

Nucleotide sequence analysis of the linked left and right hand terminal regions of adenovirus type 5 DNA present in the transformed rat cell line 5RK20. Nucleic Acids Research 10(7): 2189-2198, 1982

Nucleotide sequence analysis of the lemur beta globin gene family evidence for major rate fluctuations in globin polypeptide evolution. Molecular Biology and Evolution 3(6): 465-484, 1986

Amino terminal processing of actin in mouse l cells in vivo. Journal of Biological Chemistry 258(6): 3961-3966, 1983

Nucleotide sequence of the sheep MyoD1 gene. Nucleic Acids Research 20(2): 374-374, 1992

Partial sequence homologies between cytoskeletal proteins, c-myc, Rous sarcoma virus and adenovirus proteins, transducin, and beta- and gamma-crystallins. Bioscience Reports 5(2): 167-174, 1985

Alignment of the major tryptic fragments of the adenosine triphosphatase from sarcoplasmic reticulum. Journal of Biological Chemistry 255(14): 6562-6568, 1980

Nucleotide sequence of the listeriolysin gene from a Listeria monocytogenes serotype 1/2a strain. Nucleic Acids Research 17(15): 6406, 1989

Partial sequence homologies between cytoskeletal proteins c myc rous sarcoma virus and adenovirus proteins transducin and beta crystallins and gamma crystallins. Bioscience Reports 5(2): 167-174, 1985

Wheat gliadin fractions and other cereal antigens reactive with antibodies in the sera of celiac patients. Clinical and Experimental Immunology 50(3): 651-660, 1982

Amino-sugar modular ligands-useful cores for the formation of asymmetric copper 1,4-addition catalysts. Chemical Communications 2008(42): 5384-5386, 2008