+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

An immunohistochemical study of primary malignant lymphomas of orbital and adnexal regions

An immunohistochemical study of primary malignant lymphomas of orbital and adnexal regions

Nippon Ganka Gakkai Zasshi 92(6): 1057-1062

Immunohistochemical studies on 4 cases of primary orbital and conjunctival malignant lymphomas were reported. According to the Lymphoma Study Group classification, diffuse small cell type was found in one case, diffuse medium-sized cell type in 2 cases and diffuse mixed type in one case. Fresh biopsied materials fixed with periodate-lysate-paraformaldehy desolution for immunohistochemical study were used. Staining was performed with different monoclonal antibodies including HLA-DR, B1, B2, B4, BA-1, J5, PCA-1, Leu4, immunoglobulins, Ki-67 and alkaline phosphatase. Positive reactions for B1, B2, B4, BA-1 in 4 cases indicated B-cell origin. A positive reaction for alkaline phosphatase in 2 cases suggested that lymphoma cells might occur from mantle-zone lymphocytes. The other 2 cases were thought to be lymphomas occurring from follicular center cell. A very low positivity for Ki-67 in 4 cases suggested that lymphoma cells in the proliferating phase are extremely sparse in number.

Please choose payment method:

(PDF emailed within 1 workday: $29.90)

Accession: 004728106

Download citation: RISBibTeXText

PMID: 3263761

Related references

Primary malignant lymphomas of the orbital and adnexal regions a clinicopathologic study. Folia Ophthalmologica Japonica 39(5): 813-820, 1988

Clinicopathological and immunohistochemical study of primary orbital and conjunctival malignant lymphomas. Folia Ophthalmologica Japonica 42(6): 1330-1339, 1991

Immunohistochemical analysis of adhesion molecules and matrix metalloproteinases in malignant CNS lymphomas: a study comparing primary CNS malignant and CNS intravascular lymphomas. Brain Tumor Pathology 25(2): 73-78, 2008

Primary gastrointestinal malignant lymphomas. A morphologic and immunohistochemical study. Cancer 55(4): 870-879, 1985

Primary malignant lymphomas ml of bone an immunohistochemical and histologic study of 13 cases. Laboratory Investigation 62(1): 57A, 1990

Immunohistochemical study of 38 cases of primary ocular adnexa malignant lymphomas. Hua Xi Yi Ke Da Xue Xue Bao 26(2): 224-226, 1995

Molecular characterization of primary ocular adnexal malignant lymphomas. Investigative Ophthalmology & Visual Science 35(4): 1566, 1994

Malignant non-Hodgkin lymphomas of the orbital region. Histological classification and immunohistochemical studies. Zentralblatt für Allgemeine Pathologie U. Pathologische Anatomie 128(5-6): 339-350, 1983

Primary malignant non hodgkin lymphomas of the central nervous system a histological and immunohistochemical study of 29 cases. Neuropathology & Applied Neurobiology 16(3): 268, 1990

Development of stroma in malignant lymphomas of the brain compared with epidural lymphomas. An immunohistochemical study. Acta Neuropathologica 71(1-2): 125-129, 1986

Clinicopathologic and immunohistochemical studies of primary cutaneous malignant lymphomas. Zhonghua Pifuke Zazhi 32(Suppl. ): 40, 1999

Primary ocular adnexal lymphomas: a retrospective study of 25 patients. Leukemia and Lymphoma 54(9): 2076-2078, 2013

Orbital and adnexal lymphomas. A multiparameter approach. American Journal of Clinical Pathology 73(5): 615-621, 1980

Primary malignant lymphomas of the spleen. A morphologic and immunohistochemical analysis of 17 cases. Cancer 66(12): 2612-2619, 1990

Orbital and Adnexal Lymphomas Among Adult Patients in Ghana. Journal of the West African College of Surgeons 6(4): 136-154, 2017