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Anti glomerular basement membrane antibody and microsphere distribution in rat glomeruli



Anti glomerular basement membrane antibody and microsphere distribution in rat glomeruli



Renal Physiology 1(2): 84-92



Radiolabeled anti-glomerular basement membrane (AGBM) antibody was injected in rats and its distribution was studied in different glomerular populations by microdissection. It was compared with 15.mu.m microsphere distribution. AGBM antibody was not fully extracted in a single renal pass, precluding its use as an indicator of intrarenal plasma flow. The amount of AGBM antibody fixed in juxtamedullary glomeruli was higher than in others.

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Accession: 004757565

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