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Anti tumor cyto toxins in early stages of hepato carcinogenesis



Anti tumor cyto toxins in early stages of hepato carcinogenesis



Voprosy Onkologii (St Petersburg) 27(1): 68-72



By the cellular cytotoxic test in vitro, it was demonstrated that lymphocytes of the spleen and lymph nodes from normal mice C3HA and mice given the carcinogen o-AAT [ortho-aminoazotoluene] during 30 days show a cytotoxic effect on the hepatoma 22a culture. The cytotoxic activity of splenic and lymph node lymphocytes in mice given the carcinogen for 60 days was reduced. In a number of experiments splenic lymphocytes of these mice stimulated hepatoma 22a cell growth in vitro.

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Accession: 004760467

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