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Anticonvulsant activity of the volatile oil from the fruit of Tetrapleura tetraptera


Anticonvulsant activity of the volatile oil from the fruit of Tetrapleura tetraptera



Journal of Ethnopharmacology 18(2): 103-107



ISSN/ISBN: 0378-8741

PMID: 3560990

DOI: 10.1016/0378-8741(86)90023-1

The anticonvulsant effect of the volatile oil extracted from the fresh fruits of Tetrapleura tetraptera was investigated in mice. The results obtained show that the fresh oil given intraperitoneally offers some protection against leptazol-induced convulsions. A dose of 0.4 ml of the oil per mouse protected 78% of the animals when administered 30 min prior to leptazol. While 0.6 ml offered no protection from death, the onset of convulsions and the average time of death was prolonged.

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Accession: 004764520

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