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Approaches to the synthesis of ring c transposed progesterone analogues racemic 7 beta 15 alpha ethano 11 12 seco 11 19 bisnor 17 alpha pregn 4 ene 3 20 dione and racemic 4 4 dimethyl 7 7 ethylenedioxy 4a alpha 4b beta 8a alpha 10a beta perhydro 3 phenanthrenone



Approaches to the synthesis of ring c transposed progesterone analogues racemic 7 beta 15 alpha ethano 11 12 seco 11 19 bisnor 17 alpha pregn 4 ene 3 20 dione and racemic 4 4 dimethyl 7 7 ethylenedioxy 4a alpha 4b beta 8a alpha 10a beta perhydro 3 phenanthrenone



Journal of Organic Chemistry 52(11): 2263-2273



In an approach to the synthesis of ring C transposed progesterone derivatives rac-4,4-dimethyl-7,7-(ethylenedioxy)-(4a.alpha.,4b.beta.,8a.alpha.,10a.beta.)-perhydro-3-phenanthrenone (30) and rac-7.beta.,15.alpha.-ethano-11,12-seco-11,19-bisnor-17.alpha.-pregn-4-ene-3,20-dione (28) have been synthesized from 6-methoxytetralone. The structure of 28 has been established by X-ray crystallographic analysis.

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