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Atypical intra erythrocytic pyruvate kinase in some hematological diseases



Atypical intra erythrocytic pyruvate kinase in some hematological diseases



Scandinavian Journal of Haematology 17(1): 44-52



An atypical pyruvate kinase (PK) in erythrocytes was studied in a family with several different hematological diseases: non-spherocytic hemolysis, thrombocytopenia, myelofibrosis and polycythemic traits. Atypical intraerythrocytic PK was also found in a group of non-related patients with myelofibrosis and polycythemia vera. The atypical PK was characterized by abnormal urea inhibition and other relevant biochemical parameters.

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Accession: 004797548

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PMID: 959772


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