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Binding effects of concanavalin A on a coronavirus

Binding effects of concanavalin A on a coronavirus

Canadian Journal of Comparative Medicine 41(1): 122-126

Concanavalin A, a phytoagglutinin, binds to the envelope of hemagglutinating encephalomyelitis virus, a coronavirus. Concanavalin A treated virus suspensions lose their hemagglutination properties, and there is a transient interference with infectivity. Electron micrographs show the concanavalin A as a granular deposit adhering to the viral envelope, and there is aggregation of the virus. Concanavalin A does not bind to virions stripped of their envelopes.

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Accession: 004825626

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PMID: 832184

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