Biochemical studies on ginseng saponins 20. the effect of ginseng saponin fraction on rat hepatic microsomal ethanol oxidizing system
Tae, G.S.; Joo, C.N.
Korean Biochemical Journal 17(4): 424-430
The effect of ginseng saponin fraction on partially purified microsomal ethanol oxidizing system (MEOS) was investigated. The activity of MEOS was stimulated considerably (30% .apprx. 50%). The activity of cytochrome c reductase was also stimulated in the presence of the saponin fraction (10-5%). The conversion of cytochrome P-450 to P-420 was greatly inhibited in the presence of the saponin fraction (10-6%-10-4%) suggesting again that the MEOS was stimulated.