EurekaMag.com logo
+ Site Statistics
References:
53,869,633
Abstracts:
29,686,251
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on LinkedInFollow on LinkedIn

+ Translate

Cardiac output as a controller of ventilation through changes in right ventricular load



Cardiac output as a controller of ventilation through changes in right ventricular load



Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology 53(1): 218-224



Ventilatory responses to changes in right ventricular (RV) load were studied in spontaneously breathing anesthetized dogs. Moving average RV pressure .**GRAPHIC**. was used as an index of the RV strain. RV load was changed in 2 ways: cardiac output (.ovrhdot.Q) was increased by infusion of isoproterenol (0.7-1.2 .mu.g/min) and reduced by infusion of vasopressin (0.3-0.5 U/min); and RV pressure was increased independently of .ovrhdot.Q by partial balloon obstruction of the RV outflow. When .ovrhdot.Q was changed by drug infusion there was a linear correlation between .**GRAPHIC**. and .ovrhdot.Q (avg [average] r = 0.94). Well-correlated linear relationships were found between expired minute ventilation (.ovrhdot.VE) and .**GRAPHIC**. (avg r > 0.93), the slopes and intercepts of which were not significantly different whether .**GRAPHIC**. was changed by altering .ovrhdot.Q, partial obstruction of RV outflow, or combining both procedures. Bilateral vagotomy did not alter the .**GRAPHIC**. slope resulting from RV balloon inflations. Apparently, the RV strain may act as a controller of ventilation and provide a link between .ovrhdot.Q and .ovrhdot.VE.

(PDF emailed within 1 workday: $29.90)

Accession: 004881350

Download citation: RISBibTeXText

PMID: 7118635



Related references

Patterns of cardiac output response to acute reduction of ventricular pre load and after load pressures. American Journal of Cardiology 25(6): 662-669, 1970

Assessment of the accuracy of continuous cardiac output and pulse contour cardiac output in tracking cardiac index changes induced by volume load. Australian Critical Care 20(3): 106-112, 2007

Right ventricular pressure as a link between cardiac output and ventilation in dogs. Journal of Physiology (Cambridge) 315: 9P, 1981

Load dependence of cardiac output in biventricular pacing: right ventricular volume overload in pigs. Journal of Thoracic and Cardiovascular Surgery 128(1): 98-102, 2004

Load dependence of cardiac output in biventricular pacing: right ventricular pressure overload in pigs. Journal of Thoracic and Cardiovascular Surgery 127(6): 1713-1722, 2004

Load dependence of cardiac output in biventricular pacing: left ventricular volume overload in pigs. Journal of Thoracic and Cardiovascular Surgery 131(3): 666-670, 2006

Pulsed doppler cardiac output and left ventricular pumping ability measurements during artificial ventilation. Anesthesiology (Hagerstown) 61(3 PART A): A170, 1984

Physiological variations in the cardiac output of man IX The effect of breathing carbon dioxide, and of voluntary forced ventilation on the cardiac output of man. 1930

The ability of the Vigileo-FloTrac system to measure cardiac output and track cardiac output changes during one-lung ventilation. Journal of Clinical Monitoring and Computing 29(3): 333-339, 2016

The reproducibility of measurement of right ventricular ejection fraction and cardiac output by the thermodilution technique in patients on mechanical ventilation. Acta Anaesthesiologica Scandinavica 38(5): 486-489, 1994

Phase-related changes in right ventricular cardiac output under volume-controlled mechanical ventilation with positive end-expiratory pressure. Critical Care Medicine 27(5): 953-958, 1999

Depression of cardiac output with mechanical ventilation comparative studies of intermittent positive ventilation positive negative ventilation and assisted ventilation human. Journal of Thoracic & Cardiovascular Surgery 54(2): 182-190, 1967

Cardiac output controller. Official Gazette of the United States Patent & Trademark Office Patents 1251(1), Oct 2, 2001

The uncalibrated pulse contour cardiac output during off-pump coronary bypass surgery: performance in patients with a low cardiac output status and a reduced left ventricular function. Korean Journal of Anesthesiology 60(4): 237-243, 2011

Tomographic measurements of regional ventilation perfusion and alveolar ventilation cardiac output v a q using krypton 81m. Thorax 40(3): 233, 1985