Changes in the activities of modulator dependent protein kinases in the lungs of mice treated with butylated hydroxy toluene

Kuo, W.N.; Liu, L.P.; Mcneal, M.J.

Microbios Letters 14(55-56): 117-122


ISSN/ISBN: 0307-5494
Accession: 004912641

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Activities of modulator-dependent protein kinases (M-PK) and protamine-dependent protein kinase(s) (P-PK) increased in the lungs of mice after 6 days i.p. injections of butylated hydroxytoluene (BHT). Greater changes in the activity of lung enzymes occurred as the animals aged. These included: decreased basal, M-PK and P-PK activities in control and BHT-treated animals, and decreased ratio of BHT/control in basal enzyme activity and increased ratios in both M-PK and P-PK activities.