Section 5
Chapter 4,916

Changes in the progress of infectious diseases caused by changes of natural resistance and of steroid metabolism

Zimmermann, W.

Zentralblatt für Bakteriologie Parasitenkunde Infektionskrankheiten und Hygiene. Erste Abteilung Originale. Reihe A Medizinische Mikrobiologie und Parasitologie 244(1): 58-72


ISSN/ISBN: 0300-9688
Accession: 004915309

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The effect of steroid metabolism on infection can be modified by external influences. The average life duration of infected rabbits can be shortened by rearing a special strain of test rabbits or by lack of protein in the diet, by blocking the RES, and by treatment with cortisol, estradiol, thyroxin, glucose or polyvinylpyridine-N-oxide. Survival time is prolonged by testosterone, dehydroepiandrosterone, cryproterone, cysteine, aristolochic acid and pyrifer. No effect on the progress of an infectious disease was produced by vitamins A, B1, B6, D, E and ascorbic acid, nor by an extract of thymus gland, spleen, insulin, a preparation with STH [somatotropin], norgestrel, DMSO [dimethylsulfoxide] and treatment with Bifidobacterium bifidum and omnadin.

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