Changes in the progress of infectious diseases caused by changes of natural resistance and of steroid metabolism
Zentralblatt für Bakteriologie Parasitenkunde Infektionskrankheiten und Hygiene. Erste Abteilung Originale. Reihe A Medizinische Mikrobiologie und Parasitologie 244(1): 58-72
ISSN/ISBN: 0300-9688 Accession: 004915309
The effect of steroid metabolism on infection can be modified by external influences. The average life duration of infected rabbits can be shortened by rearing a special strain of test rabbits or by lack of protein in the diet, by blocking the RES, and by treatment with cortisol, estradiol, thyroxin, glucose or polyvinylpyridine-N-oxide. Survival time is prolonged by testosterone, dehydroepiandrosterone, cryproterone, cysteine, aristolochic acid and pyrifer. No effect on the progress of an infectious disease was produced by vitamins A, B1, B6, D, E and ascorbic acid, nor by an extract of thymus gland, spleen, insulin, a preparation with STH [somatotropin], norgestrel, DMSO [dimethylsulfoxide] and treatment with Bifidobacterium bifidum and omnadin.