Section 5
Chapter 4,926

Characterization of a protein kinase-phosphoprotein system in free cytoplasmic ribonucleoprotein particles of plasma cell tumours

Egly, J.M.; Schmitt, M.; Kempf, J.

Biochimica et Biophysica Acta 454(3): 549-557


ISSN/ISBN: 0006-3002
PMID: 187238
Accession: 004925496

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A protein kinase associated with free cytoplasmic ribonucleoprotein particles (free dRNP) was purified from mouse plasma cell tumors. This protein kinase phosphorylates endogenous protein from free dRNP in vitro. Some characteristics of this protein kinase were studied. This protein kinase is cyclic AMP independent. The properties of this protein kinase were compared with other protein kinases: soluble, ribosome bound and nuclear protein kinases. Although there are minor differences it is very similar to a ribosome associated protein kinase from the plasma cell tumors.

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