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Cimetidine vs. a combination of antacid and anticholinergic for hospitalized patients with gastric ulcer

Cimetidine vs. a combination of antacid and anticholinergic for hospitalized patients with gastric ulcer

Gastroenterologia Japonica 20(1): 1-5

Inpatients (185) with ulcer in the gastric corpus and angle were treated with either 1 g cimetidine per day or with a combination of antacid and anticholinergic. At 2, 4, 6 and 8 wk after entry into the study, the ulcer had healed in 3.3, 30.4, 55.4 and 87.0% of patients treated with cimetidine, as compared with 0, 12.9, 51.6 and 73.1% of those treated with a combination of antacid and anticholinergic (NS [not significant], P < 0.01, NS., P < 0.05), respectively. Factors that had a delaying effect on ulcer healing were seen more frequently in the cimetidine group. Cimetidine was superior to a combination of antacid and anticholinergic, for the treatment of gastric ulcer.

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Accession: 004957798

Download citation: RISBibTeXText

PMID: 4018493

DOI: 10.1007/bf02774667

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