Ciruclation in the head and intra-ocular pressure. An analysis of the correlation and interactions between blood pressure, blood flow, osmotic pressure, hematocrit and intra-ocular pressure
Kaskel, D.; Fink, H.
Documenta Ophthalmologica. Advances in Ophthalmology 42(2): 241-301
ISSN/ISBN: 0012-4486 PMID: 862510 Accession: 004960694
The influence of some biophysical factors on intraocular pressure (IOP) was measured by perfusion experiments using the isolated rabbit head. Perfusion pressure, osmotic concentration, hematocrit and oxygenation were varied. The influence of perfusion pressure on IOP decreased the more the perfusion liquid resembled blood. The influence of hematocrit on IOP was small and depended on the common carotid perfusion flow. The IOP was increased with body weight in animals with a body weight between 1-2.5 kg. In most experiments the IOP during perfusion was directly proportional to the initial value, so that the initial value was determinant for the IOP-level during the whole experiment.