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Clinical results of intra aortic balloon pumping in 51 patients following cardiac surgery



Clinical results of intra aortic balloon pumping in 51 patients following cardiac surgery



Journal of the Japanese Association for Thoracic Surgery 33(3): 291-297



IABP [intra-aortic balloon pumping] for perioperative low cardiac output syndrome (LOS) and the linger period of IABP with or without concomitant use of myocardial protective agents such as lidocaine, coenzyme Q10 (CoQ10) and aprotinin on complications and survival rate were examined. Adult patients (51) who developed left ventricular failure following various cardiac surgery were subjected in this investigation. Eight patients died of LOS because of unsuccessful weaning from IABP. Only 2 patients died in the hospital because of respiratory failure and nonoliguric renal failure but no hospital deaths were noted in relation to LOS in the survival patients. Survival rate was as follows: 67% in the cases treated with IABP at emergency operation for cardiogenic shock, 77% in the patients who were unable to be weaned from cardiopulmonary bypass (CPB) and 79% in the patients who were weaned from CPB but needed IABP for treatment of LOS. The duration of IABP support was 1-28 days (mean 5.3 days) in survivors from IABP but only 3 patients (7%) sustained complications related to use of the IABP. There was no significant correlation between the incidence of complications and duration of IABP support. The longer period of IABP support appears to be mandatory without raising the frequency of complications. Fifty-one patients were divided into 2 groups. Group I (30 patients) was treated by IABP only and group II (21 patients) was treated by the concomitant use of lidocaine, coenzyme Q10 and aprotinin with IABP. Lidocaine was infused continuously 1-2 mg/min, aprotinin and CoQ10 were administrated 5000-10,000 kU/kg per day and 5-10 mg/day, respectively. Successful weaning rate from IABP was 95% (20/21) in group II and was higher than that of 77% (23/30) in group I. There were no significant differences in parameters between 2 groups concerning the preoperative and postoperative factors except a lower rectal temperature. Concomitant use of lidocaine, CoQ1o and aprotinin with IABP leads to an improvement in postoperative LOS.

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Accession: 004971400

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PMID: 2410517


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