+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Colonization of the upper jejunum by entero pathogenic and entero toxigenic escherichia coli in pediatric diarrhea



Colonization of the upper jejunum by entero pathogenic and entero toxigenic escherichia coli in pediatric diarrhea



Acta Paediatrica Scandinavica 71(3): 457-466



Aspirated fluid from the upper jejunum was obtained by intubation of 27 children with diarrhea and 7 control children without diarrhea. The aspirated jejunal fluid was analyzed for total counts of viable aerobic and anaerobic microorganisms. Gram-negative aerobic bacteria were typed biochemically and analyzed for the production of heat-labile and heat-stable enterotoxins. Enteropathogenic E. coli (EPEC) strains of serogroups 0111, 055 and 0127 were detected in the stools of 9 patients and the respective strains concomitantly in the upper jejunum (103-108 bacteria/ml) in 7 patients with diarrhea. In 6 patients from whom isolates of enterotoxigenic E. coli (ETEC) were obtained, there were high total viable counts of non-enterotoxigenic bacteria in the upper jejunum and ETEC were recovered from this location in 3 cases. Enterotoxigenic Klebsiella was recovered from feces but not from the upper jejunum in 1 case. Compared to the controls, the total number of bacteria in the upper jejunum was 100-1000 times higher in patients with enteropathogenic E. coli (EPEC) or enterotoxigenic E. coli (ETEC). In another 11 cases with diarrhea caused by Shigella, rotavirus or of unknown etiology, the total viable counts of bacteria were similar to those of the controls. Five patients with severe EPEC diarrhea received antibiotics for 5 days. The patients improved clinically; the EPEC strain had disappeared from the upper jejunum when they were reexamined. Thus, in EPEC diarrhea, a colonization of the upper jejunum by the causative organism seemed to take place; in ETEC diarrhea, there appeared to be a nonspecific contamination by enteric bacteria.

Please choose payment method:






(PDF emailed within 1 workday: $29.90)

Accession: 004985278

Download citation: RISBibTeXText


Related references

Frequency of the isolation of entero pathogenic and entero toxigenic escherichia coli from adult diarrhea patients. Zhurnal Mikrobiologii Epidemiologii i Immunobiologii (2): 70-73, 1982

Colonization of porcine intestine by entero toxigenic escherichia coli selection of piliated forms in vivo adhesion of piliated forms to epithelial cells in vitro and incidence of a pilus antigen among porcine entero pathogenic escherichia coli. Infection and Immunity 16(1): 344-352, 1977

Identification of entero toxigenic escherichia coli in patients with diarrhea in asia with 3 entero toxin gene probes. Infection & Immunity 42(1): 152-155, 1983

Biological characteristics of entero pathogenic and entero toxigenic escherichia coli. Zhurnal Mikrobiologii Epidemiologii i Immunobiologii (6): 61-64, 1981

Evidence for a 2nd colonization factor antigen of entero toxigenic escherichia coli causing diarrhea in man. Abstracts of the Annual Meeting of the American Society for Microbiology 78 : 15, 1978

Pathogenic effect of entero toxigenic escherichia coli and escherichia coli causing infantile diarrhea. Acta Microbiologica Academiae Scientiarum Hungaricae 24(3): 221-236, 1977

Vaccination against entero toxigenic escherichia coli induced diarrhea with purified colonization factor antigens in man. Gastroenterology 86(5 PART 2): 1096, 1984

Serological evidence for the role of colonization factor antigens in entero toxigenic escherichia coli diarrhea of travelers. Abstracts of the Annual Meeting of the American Society for Microbiology 78 : 279, 1978

Several serotypes of entero toxigenic escherichia coli and reovirus like agents in pediatric diarrhea. Pediatric Research 12(4 PART 2): 491, 1978

Experimental diarrhea in baby rabbits due to oral administration of heat labile entero toxin of escherichia coli entero pathogenic for swine. Acta Veterinaria Academiae Scientiarum Hungaricae 24(1-2): 177-186, 1974

Immuno protein against entero toxigenic escherichia coli diarrhea in rabbits by per oral administration of purified colonization factor antigen. FEMS Microbiology Letters 11(4): 303-308, 1981

The role of reovirus like agent and heat labile entero toxigenic escherichia coli in pediatric diarrhea. Pediatric Research 10(4): 399, 1976

Association of plasmid mediated antibiotic resistance and entero toxigenic escherichia coli and reovirus like agents in pediatric diarrhea. Pediatric Researchpart 2: 491, 1978

Comparison of entero toxic activity of heat stable entero toxin from porcine class i and class ii strains of entero toxigenic escherichia coli. Gastroenterology 78(5 PART 2): 1290, 1980

Distribution of entero pathogenic escherichia coli in oyster farm areas relation of escherichia coli most probable number estimate to entero pathogenic escherichia coli contamination. Journal of the Food Hygienic Society of Japan 21(1): 5-12, 1980