Combined action of thio phosphamide and dipine on chromosomes of human lymphocytes
Yakovenko, K.N.; Nazarenko, S.A.
Tsitologiya i Genetika 11(4): 347-350
Separate and combined action of thiophosphamide and dipine on chromosomes of human lymphocytes is analyzed. A method is suggested for controlling the additivity of the combined action of the mutagens taking into consideration a nonlinear dependence of the cytogenetic effect on the concentration. The inadequacy of the traditional experimental scheme when studying this problem is emphasized.