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Combined effect of fluoride retention in dental enamel treated with topical fluoride application and fluoride dentifrices


Combined effect of fluoride retention in dental enamel treated with topical fluoride application and fluoride dentifrices



Shika Igaku 49(4): 445-474



It has been reported that most of the incorporated fluoride which was applied topically will leach out of the dental enamel. In this study, it was found that the uptake and retention of fluoride in the surface enamel was effectively increased by the combined treatment of acidulated phosphate fluoride (APF) and fluoride dentifrices. The wax window method was performed on bovine enamel sections. Three kinds of fluoride materials, SnF2, SnF2 phytate and monofluorophosphate, were used as the dentifrice additives, and the control dentifrice was prepared without any fluoride. When the enamel was treated using fluoride dentifrices every day following a soaking in an APF solution, the uptake of fluoride in the enamel surface was increased to 5 to 6 times that of treatment with only fluoride dentifrices, and to 1.4 times that of treatment with only the APF solution. Moreover, the retention of fluoride with combined treatments was higher than that with the individual treatments for all experimental periods. The fluoride uptake and retention in enamel were independent of the kind of fluoride dentifrice. From these findings, it is suggested that the combined treatment of topical fluoride application and fluoride dentifrices could be clinically effective in prevention of dental caries.

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