EurekaMag.com logo
+ Site Statistics
References:
53,869,633
Abstracts:
29,686,251
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on LinkedInFollow on LinkedIn

+ Translate

Combined effects of light and acute ischemia on the structure of the rabbit retina a light microscopic and electron microscopic study



Combined effects of light and acute ischemia on the structure of the rabbit retina a light microscopic and electron microscopic study



Investigative Ophthalmology & Visual Science 22(4): 449-459



The ultrastructure of the rabbit retina was investigated to determine the combined effects of light and ischemia. Both eyes of 16 adult Dutch rabbits were exposed to light of an intensity known to be near or below the threshold for ultrastructural changes in the retina. One eye of each animal was subjected to 1 of 4 periods of pressure-induced total acute ischemia. Exposure to light alone resulted in only minor disturbances of the receptor cell outer segments. The remainder of the retina was of normal morphologic appearance. Exposure to the combined insults of light exposure and ischemia produced considerably more damage to the inner and outer retina. Light exposure combined with short periods of ischemia (15-30 min) resulted in edema of the pigment epithelium and disturbances of the receptor cell inner and outer segments. Light exposure combined with longer ischemic periods (45-60 min) resulted in severe disturbances in the structure of the pigment epithelium, breakdown of the receptor cell outer segments, rupture of the inner segment mitochondria and severe exema of the neural retina. The implication of this addictive or synergistic action of light and ischemia is discussed.

(PDF emailed within 1 workday: $29.90)

Accession: 004988084

Download citation: RISBibTeXText



Related references

The combined effects of light and acute ischemia on the structure of the rabbit retina: a light and electron microscopic study. Investigative Ophthalmology & Visual Science 22(4): 449-459, 1982

Light microscopic and electron microscopic study on rabbit retina after krypton or argon laser photo coagulation. Journal of Nara Medical Association 31(2): 170-179, 1980

A light microscopic and electron microscopic study of the structure of the retina of the harp seal pagophilus groenlandicus. Rapports Et Proces Verbaux Des Reunions Conseil International Pour L'Exploration De La Mer: 2-96, 1975

Observations on tissue grafts established in rabbit ear chambers a combined light microscopic and electron microscopic study. Journal of Experimental Medicine 134(4): 963-985, 1971

Combining light microscopic and electron microscopic findings on individual cells a theoretical and methodological study exemplified by combined electron microscopy and light microscope auto radiography. Microscopica Acta 75(1): 48-60, 1973

The structure of the developing and adult ciliary complex of the rabbit eye a gross light microscopic and electron microscopic study. Documenta Ophthalmologica 28(2): 205-373, 1970

The pleura a combined light microscopic scanning electron microscopic and transmission electron microscopic study in the sheep 2. response to injury. Experimental Lung Research 5(2): 125-140, 1983

Transmission electron microscope study of the combined effects of light and ischemia on the rabbit retina. Ophthalmic Research 10(5-6): 339, 1978

Comparative light microscopic and electron microscopic study of the human dog and rat prostate an approach to an experimental model for human benign prostatic hyperplasia light microscopic and electron microscopic analysis a review. Urologia Internationalis 35(2): 91-104, 1980

The cellular origin and development of atheromatous plaques a light microscopic and electron microscopic study of combined x ray and hyper cholesterolemia induced atheromatosis in the carotid artery of the rabbit. Virchows Archiv B Cell Pathology Including Molecular Pathology 43(1): 1-16, 1983

Effects of anti oxidant nutrient deficiency on the retina and retinal pigment epithelium of albino rats a light microscopic and electron microscopic study. Experimental Eye Research 34(3): 339-370, 1982

Effects of gentamicin on rabbit organ cultured corneal endothelia light microscopic and electron microscopic study. Folia Ophthalmologica Japonica 32(6): 1306-1312, 1981

Development of type i cells of the rabbit subclavian glomera aortic bodies a light microscopic fluorescence microscopic and electron microscopic study. American Journal of Anatomy 153(1): 15-32, 1978

Combined macroscopic light microscopic scanning electron microscopic and transmission electron microscopic investigation of the vitreous body 3. structure of the anterior border layer of the vitreous. Ophthalmic Research 15(1): 11-18, 1983

The fine structure of the head epidermis of juvenile rainbow trout salmo gairdneri a light microscopic transmission electron microscopic and scanning electron microscopic study. Zoologischer Anzeiger 207(1-2): 1-15, 1981