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Comparative study between 3 methods for quinidine determination in plasma

Streit Barsotti, D.; Lacroix, R.; Lacroix, J.

Journal de Pharmacie Clinique 3(3-4): 359-366

1984


ISSN/ISBN: 0291-1981
Accession: 004999793

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Three methods of quinidine determination in plasma were compared: double extraction spectrofluorometric technique (CANAL-FLOUVAT); homogeneous fluorescent immunoassay (AMES); and homogeneous enzyme immunoassay (EMIT). The results showed good linearity of the calibration curve and satisfactory precision without a significant difference between the 3 methods. The results given by these techniques correlated well, but EMIT values were lower than those found with the 2 other methods.

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