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Compound effects of bisulphite ion on frog skeletal muscle



Compound effects of bisulphite ion on frog skeletal muscle



Biochemical Pharmacology 34(5): 637-640



To characterize the structures of the nicotinic cholinoceptors in the frog rectus abdominis muscle, group-selective reagents were used. Possible modifications of the excitation-contraction coupling were also studied. The effect of the bisulfite ion on skeletal muscle was demonstrated earlier at presynaptic and postsynaptic levels. Bisulfite induced qualitative and quantitative changes in the muscular response to acetylcholine and electrical stimulation. The intervention is likely at the level of excitation-contraction coupling as well as at the previously proposed sites.

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Accession: 005024142

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PMID: 3872127


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