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Computation techniques for rebreathing lung tissue volume and pulmonary capillary blood flow



Computation techniques for rebreathing lung tissue volume and pulmonary capillary blood flow



Journal of Applied Physiology Respiratory Environmental & Exercise Physiology 52(5): 1375-1377



The end-tidal, dead-space-corrected (ETDS) and the multiple-point, zero-forcing (MPZF) techniques for calculating lung tissue volume (Vt) and pulmonary capillary blood flow (.ovrhdot.Qc) were compared in 102 acetylene rebreathing measurements in 10 stable, intact dogs. There was no statistical difference by paired t test between the 2 methods of computing Vt. Pulmonary capillary blood (.ovrhdot.Qc) computed by the MPZF technique was significantly larger (11%) than .ovrhdot.Qc computed by the ETDS technique. Neither computational technique significantly improved the reproducibility (coefficient of variation) of repeated measurements of Vt or .ovrhdot.Qc. In dogs these 2 computation techniques produce equivalent values and have equivalent reproducibility for rebreathing determinations of Vt with acetylene.

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Accession: 005024630

Download citation: RISBibTeXText

PMID: 7096158

DOI: 10.1152/jappl.1982.52.5.1375


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