Cyto genetic effect of some pesticides in human peripheral lymphocyte culture under different initial levels of chromosome aberrations

Pilinskaya, M.A.

Tsitologiya i Genetika 15(2): 82-84


Accession: 005081710

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The mutagenic activity of pesticides (polymarzin, cuprozin and pyrimor) were studied in the human peripheral lymphocyte culture at various frequencies of spontaneous chromosome aberrations. Only pyrimor is determined to possess the cytogenetic action in the test-system. The intensity of the pyrimor-induced cytogenetic effect depends on the initial level of aberrant metaphases in the control cultures obtained from 2 different persons. The potential mutagenic danger of pyrimor is confirmed as previously based on studies of its cytogenetic activitiy in mice bone marrow cells.