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Depressant effect of forskolin on spontaneous locomotor activity in mice

Depressant effect of forskolin on spontaneous locomotor activity in mice

General Pharmacology 16(5): 521-524

Forskolin, an activator of adenylate cyclase, depressed spontaneous locomotor activity when injected intracerebroventricularly into mice in doses of 10 and 100 .mu.g. The findings suggest that increases in brain cAMP levels may be associated with a reduction in excitability.

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Accession: 005108259

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PMID: 2996973

DOI: 10.1016/0306-3623(85)90016-3

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