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Detection of antibodies against human influenza a virus h1n1 in swine sera in west germany



Detection of antibodies against human influenza a virus h1n1 in swine sera in west germany



Journal of Veterinary Medicine Series B 35(6): 474-476



213 sera collected from slaughtered pigs in Hassia (FRG) from December 1987 were tested for antibodies against influenza A virus (subtype H1N1) using the single radial haemolysis technique (SRHT). Eight sera (3.7%) contained antibodies against influenza A virus A/Singapore/6/86 (H1N1) and three of them were simultaneously positive for antibodies to A/Swine/Arnsberg/1/81 (H1N1). Absorption tests with both H1N1 virus strains removed detectable homologous antibodies, but failed to remove heterologous antibodies, although a minor cross-reaction between both strains was sometimes found. The results strongly suggest that the pigs became infected with the human influenza virus H1N1 strain A/Singapore/6/86, recently known to be prevalent in the human population. This is the first report about antibodies to human influenza A virus, subtype H1N1, in pigs in the Federal Republic of Germany.

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Accession: 005115485

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