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Detection of antigens immunologically related to envelope antigens of mouse mammary virus in human mammary gland carcinoma tissues

Kryukova, I.N.; Komarova, E.A.

Voprosy Virusologii 1: 56-61

1980


ISSN/ISBN: 0507-4088
Accession: 005115673

A highly sensitive method of electroimmunodiffusion in acetate cellulose films was used for the detection of an antigen related to envelop antigens of mouse mammary tumor virus (MMTV) in human mammary gland carcinoma (HMGC) tissues. In 4 of 10 HMGC cases, fractions of proteins with MW of .apprx. 50,000 daltons, previously isolated in polyacrylamide gels with sodium dodecyl sulfate, contained an antigen reacting with antiserum to p52 of MMTV. The immunological identity of both antigens was thus shown.

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