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Differences in the ability of human peripheral blood monocytes and in vitro monocyte derived macrophages to produce super oxide anion studies with cells from normals and patients with chronic granulomatous disease

, : Differences in the ability of human peripheral blood monocytes and in vitro monocyte derived macrophages to produce super oxide anion studies with cells from normals and patients with chronic granulomatous disease. Journal of the Reticuloendothelial Society 31(3): 261-266

Monocytes from normals and patients with chronic granulomatous disease (CGD) and macrophages derived from these monocytes were examined for their ability to produce superoxide anion O2. The response of normal monocytes increased 2.5 to 3-fold by day 3-5 in culture and then decreased, at a time when other cellular functions continued to increase. CGD monocytes never developed the capacity to release.

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Accession: 005151050

PMID: 6281432

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