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Differences in the concanavalin induced re distribution and agglutination patterns of epstein barr virus genome free and epstein barr virus carrying human lymphoma lines

, : Differences in the concanavalin induced re distribution and agglutination patterns of epstein barr virus genome free and epstein barr virus carrying human lymphoma lines. Experimental Cell Research 108(1): 185-190

EBV[Epstein-Barr virus]-carrying human lymphoid lines showed a reduced redistribution of concanavalin A (ConA) receptors after ligand contact, compared with EBV negative lines. ConA agglutinability showed the opposite pattern, high in EBV-positive, low in EBV-negative lines. The same differences were also found in a comparison between 2 EBV-negative lines and their in vitro EBV-converted, viral genome-carrying sublines, suggesting that the viral genome is directly responsible.

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