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Differences in the formation of permanent estrus in rats after autotransplantation of the ovaries and other procedures

, : Differences in the formation of permanent estrus in rats after autotransplantation of the ovaries and other procedures. Byulleten' Eksperimental'noi Biologii i Meditsiny 100(9): 341-342

In adult female rats, constant light leads to the cessation of the sexual cycle and formation of permanent estrus after 6 to 7 days. In young animals, the sexual cycle was retained despite constant light and only after 3 months when the body weight of the rats reached 200-220 g the estrus became permanent. This happened earlier than in animals with the ovaries autotransplanted to the ears. The combination of constant light and autotransplantation of the ovaries caused an earlier formation of permanent estrus. It is marked that the same mechanism (the age-associated decrease of the cyclic center sensitivity to estrogen) underlies permanent estrus of various etiology.

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