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Differences in the poly peptide composition of virulent and avirulent newcastle disease virus strains during reproduction in chick embryo fibroblast cultures

, : Differences in the poly peptide composition of virulent and avirulent newcastle disease virus strains during reproduction in chick embryo fibroblast cultures. Voprosy Virusologii (4): 403-410

The loss of the capacity for secondary infection of the cells in reproduction of avirulent Newcastle disease virus strains in chick embryo fibroblast [CEF] cultures was found. This loss was associated with changes in the polypeptide composition of the virions. In virions of the avirulent Queensland strain incapable of infection CEF cultures an additional polypeptide was found with MW of 67,000 daltons which was lacking in virions of the virulent Beaudette strain and corresponded to F0 protein of paramyxoviruses.

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