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Differences in the properties of antibodies and natural anti globulin reactants revealed by human immuno globulin g chemical modification


, : Differences in the properties of antibodies and natural anti globulin reactants revealed by human immuno globulin g chemical modification. Byulleten' Eksperimental'noi Biologii i Meditsiny 88(11): 585-587

The naturally-occurring antiglobulin factors, homoreactants, contained by human Ig[immunoglobulin]G preparations, are inactivated as a result of incubation in a solution of sodium rhodanide (3-5 M) and sodium desoxycholate (0.005 M). Staphylococcal antitoxin contained by the same human IgG preparations is resistant to the action of the reagents. The differences in the structure of homoreactants and antibodies are indicated.

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