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Differences in the response of human and rat blood to l dopa and 5 hydroxy l tryptophan in vitro biochemical and histochemical data


, : Differences in the response of human and rat blood to l dopa and 5 hydroxy l tryptophan in vitro biochemical and histochemical data. Journal of Clinical Chemistry and Clinical Biochemistry 16(1): 5-10

When incubated with whole human blood at ordinary temperature, L-dopa remains unchanged for at least 30 min. Under the same experimental conditions, 5-hydroxy-L-tryptophan shows a tendency to decrease. When incubated with blood from pentobarbital anesthetized rats, these aminoacids decrease to about 50% of the added quantity in less than 5 min; thereafter, their level remains stable (L-dopa) or slowly decreases (5-hydroxy-L-tryptophan).

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