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Differences in the segmental flexibility and local conformational mobility of lateral groups spin labeled molecules of two immunoglobulin g subclasses from the blood serum of ill and healthy cows


, : Differences in the segmental flexibility and local conformational mobility of lateral groups spin labeled molecules of two immunoglobulin g subclasses from the blood serum of ill and healthy cows. Biofizika 32(3): 514-516

The segmental flexibility of molecules from two IgG subclasses of cows' blood serum was first observed. It was shown that IgG1 molecule has a more flexible hinge region than IgG2 molecule and lower local conformational stability. At the same time the states of IgG1 and IgG2 molecules determined by dynamic-steric characteristics for ill and healthy cows practically did not differ.

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