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Differences in the segmental flexibility and local conformational mobility of lateral groups spin labeled molecules of two immunoglobulin g subclasses from the blood serum of ill and healthy cows


Biofizika 32(3): 514-516
Differences in the segmental flexibility and local conformational mobility of lateral groups spin labeled molecules of two immunoglobulin g subclasses from the blood serum of ill and healthy cows
The segmental flexibility of molecules from two IgG subclasses of cows' blood serum was first observed. It was shown that IgG1 molecule has a more flexible hinge region than IgG2 molecule and lower local conformational stability. At the same time the states of IgG1 and IgG2 molecules determined by dynamic-steric characteristics for ill and healthy cows practically did not differ.


Accession: 005151584



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