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Differences in the structure of adrenaline and acth receptors in adipose cells of rats

Byulleten' Eksperimental'noi Biologii i Meditsiny 88(11): 539-540

Differences in the structure of adrenaline and acth receptors in adipose cells of rats

Treatment of adipose tissue of the rat epididymis with trypsin decreased the lipolytic action of ACTH by 95% and the lipolytic action of adrenaline [epinephrine, E] by 50%. Supplementation of the incubation sample with lysolecithin suspension led to a complete loss of the tissue sensitivity to ACTH and a 40% decrease in the sensitivity to E. A conclusion is made about the different structures of E and ACTH-receptors in the plasma membrane of adipose cells.

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Accession: 005151616

PMID: 231984

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