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Different amount of calorie intake in the incidence and growth of methylnitrosourea induced mammary carcinoma in rats with some biochemical parameters

, : Different amount of calorie intake in the incidence and growth of methylnitrosourea induced mammary carcinoma in rats with some biochemical parameters. Hacettepe Medical Journal 20(2): 59-68

In this study in which three groups of female Sprague-Dawley rats with MNU-induced mammary tumour were given diets containing 30, 40 or 50 Kcal/day, the effect of these calories on the tumour incidence and growth, plasma and liver lipids, vitamins A and E, were investigated. Feeding different amounts of energy did not effect on tumour incidence. The levels of plasma lipids and the vitamins were not altered. Nevertheless, the liver vitamin E was decreased during aging, while the vitamin A in the liver increased.

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