+ Site Statistics
+ Resolve Accession
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
Submit PDF Full TextSubmit PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Different autochthonous models of colorectal cancer in the rat

, : Different autochthonous models of colorectal cancer in the rat. Journal of Cancer Research & Clinical Oncology 111(2): 157-159

Chemically induced (autochthonous) tumors in the rodent are thought to be the best models at hand to obtain results transferable to the clinical situation. Four different autochthonous tumor models: 1,2-dimethylhydrazine, N-methylnitrosourea (MNU), N-methyl-N-nitro-nitrosoguanidine (MNNG), and N-nitroso-acetoxymethyl-methylamine (AMMN) which are used worldwide for etiological and therapy studies of colon cancer are compared for tumor biology and clinical relevance. The four tumor models of colon carcinoma described in the rat are different in growth, invasion, and metastases. The choice of the selected tumor model for experimental investigations of colon cancer should depend on the clinical question.

Order PDF Full Text


Click here to order any other PDF Full Text

Accession: 005151894

PMID: 3700460

DOI: 10.1007/bf00400756

Download PDF Full Text: Different autochthonous models of colorectal cancer in the rat

Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:

Other references

Won, S.; Kim, S.; Elston, R.C., 2009: Phase uncertainty in case-control association studies. The possible evidence for association comprises three types of information: differences between cases and controls in allele frequencies, in parameters for Hardy-Weinberg disequilibrium (HWD), and in parameters for linkage disequilibrium (LD). LD...

Papadopoulos, O.N.; Chrisostomidis, C.I.; Georgiou, P.N.; Frangoulis, M.B.; Zapantis-Fragos, M.K.; Champsas, G.G., 2005: Vertical trapezius musculocutaneous flap: a retrospective study. From 1986 to 2001, 17 patients (aged 26-77 years) were treated using the vertical trapezius musculocutaneous flap. A two-stage procedure was used in 7 and a single-stage island flap in 10. The donor site was closed directly in all patients. Mean l...

Biti, G.P.; Magrini, S.M.; Villari, N.; Caramella, D.; Guazzelli, G.; Rosi, A.; Lippi, A., 1989: Brain damage after treatment for acute lymphoblastic leukemia. A report on 34 patients with special regard to MRI findings. In 34 patients treated for acute lymphoblastic leukemia (ALL), central nervous system (CNS) damage was assessed by clinical evaluation and brain magnetic resonance imaging (MRI). Twenty-seven of them had been off therapy from 5 to 109 months (medi...

Buchholtz, E.A.; Booth, A.C.; Webbink, K.E., 2007: Vertebral anatomy in the Florida manatee, Trichechus manatus latirostris: a developmental and evolutionary analysis. The vertebral column of the Florida manatee presents an unusual suite of morphological traits. Key among these are a small precaudal count, elongate thoracic vertebrae, extremely short neural spines, lack of a sacral series, high lumbar variabili...

Boeck A.; Forchhammer K.; Heider J.; Baron C., 1991: Selenoprotein synthesis an expansion of the genetic code. A number of enzymes employ the unusual amino acid selenocysteine as part of their active site because of its high chemical reactivity. Selenocysteine is incorporated into these proteins co-translationally: biosynthesis occurs on a specific tRNA an...

Hudd, R.; Kalax, P., 1998: Effects of acidification on 0+ juvenile fish diversity and abundance in River Kyronjoki, Finland. Italian Journal of Zoology Modena 65: 483-486 (Suppl)

Makings, P.H.ssain, C., 1970: The orientation of locusts to a lamp after unilateral injury. Journal of experimental biology: 52 (2) 447-454

Fagerson, M.H.; Barmack, N.H., 1993: Activity of single neurons in nucleus reticularis gigantocellularis of rabbit evoked by vestibular otolithic stimulation. Society for Neuroscience Abstracts 19(1-3): 139

Bruse, G.W.; Wollin, R.; Lindberg, A.A., 1989: Interaction between phage G13 and its oligosaccharide receptor studied by equilibrium dialysis. The reversible binding of phage G13, a phi X174-like single-strand DNA phage, to a 3H-labelled nonasaccharide from the lipopolysaccharide of its natural host Escherichia coli C was studied with equilibrium dialysis. The binding constant (Ka) was d...

Muma, J.R., 1975: The communication game: dump and play. Communication entails much more than formulating a linguistic code to map underlying intents. It entails the utilization of a role-taking attitude in reconciling communicative obstacles that arise from significant speaker-listener discrepancies in...