+ Translate

Different classes of antibody activities to trichosporon cutaneum antigen in summer type hypersensitivity pneumonitis by elisa

, : Different classes of antibody activities to trichosporon cutaneum antigen in summer type hypersensitivity pneumonitis by elisa. American Review of Respiratory Disease 133(1): 83-87

To assess the diagnostic value of antibody activities to Trichosporon cutaneum antigen in patients with summer-type hypersensitivity pneumonitis in Japan, we measured the serum IgG, IgA, and IgM antibodies to saline-soluble antigen of homogenized T. cutaneum cells by enzyme-linked immunosorbent assay (ELISA). The IgG antibody activity was observed in serum samples from 25 (83%) of the 30 patients and in 9 (82%) of the 11 asymptomatic family members. The IgA antibody activity was found in 25 (83%) of the patients but in only 3 (27%) of asymptomatic family members. Unexpectedly, we found no significant correlation between the IgG and IgA antibody activities to the same antigen in individual patients. Moreover, although the IgG antibody activity was related to the precipitating antibody, the IgA antibody activity was not. The IgM antibody activity by ELISA was found in only 5 (17%) of the patients. The IgG+IgA+IgM antibody activity was demonstrated in 27 (90%) of the 30 patients, and of 3 serum samples that were found negative by the ELISA method, 2 were positive by the IFA method. We conclude that the detection of the serum IgG and IgA antibody activities to T. cutaneum antigen by ELISA is a simple and useful serodiagnostic test for summer-type hypersensitivity pneumonitis. Measurement of the IgA antibody activity is especially helpful in discriminating symptomatic from asymptomatic family members.

(PDF 0-2 workdays service)

Order PDF Full Text


Click here to order any other PDF Full Text

Accession: 005151999

PDF Full Text: Submit

Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:

Other references

Teich, Y; Neumark, S., 1977: A net work of pheromone traps effectively reduces the number of treatments against Spodoptera littoralis. Hassadeh 57 (6) 1162-1165

Barendse, G. W. M.; Dijkstra, A.; Moore, T. C., 1983: The biosynthesis of the gibberellin precursor ent-kaurene in cell-free extracts and the endogenous gibberellins of Japanese morning glory in relation to seed development. The endogenous levels of gibberellins determined by a combined HPLC-bioassay procedure and the formation of ent-kaurene, an immediate GA precursor, in cell-free extracts were studied in relation to seed development in Pharbitis nil cv. Violet. Thr...

Korner, Anneliese F.; Stevenson, David K.; Forrest, Thomas; Constantinou, Janet C.; Dimiceli, Sue; Brown, Byron W.Jr, 1994: Preterm medical complications differentially affect neurobehavioral functions Results from a new neonatal medical index. Infant Behavior & Development 17(1): 37-43

Anonymous, 2013: The Supermassive Black Hole Mass - Spheroid Stellar Mass Relation for S\ersic and Core-S\ersic Galaxies. We have examined the relationship between supermassive black hole mass (M_BH)and the stellar mass of the host spheroid (M_sph,*) for a sample of 75 nearbygalaxies. To derive the spheroid stellar masses we used improved 2MASS K_s-bandphotometry fro...

Doggett, Teresa A.; Brown, Peter K., 1996: Attenuated Salmonella as vectors for oral immunization. Kiyono, H [Editor], Ogra, P L [Editor], McGhee, J R [Editor] Mucosal vaccines : 105-118

Chuang, Chun-Yu; Chang, Chen-Chen, 2007: Urinary 1-hydroxypyrene level relative to vehicle exhaust exposure mediated by metabolic enzyme polymorphisms. Taiwan-Polycyclic aromatic hydrocarbons (PAH) are common air pollutants generated from incomplete combustion. The inhalation of exhaust fumes in urban areas has been suggested to be an additional contributing factor. This study investigated the i...

Greisman S.G.; Redecha P.B.; Kimberly R.P.; Christian C.L., 1987: Differences among immune complexes association of c1q in sle immune complexes with renal disease. Studies that made use of multiple assay systems demonstrated increased levels of immune complexes (IC) in patients with systematic lupus erythematosus (SLE), but no consistent correlations of IC concentration to pattern or activity of disease have...

Yu, Shi Yuan; Si, Ke Yuan; Wang, Zi Ren; Wang, Jian Lin, 2002: SEM observations on the microvasculature of the renal glomerulus of Chrysolophus pictus and the mouse. In order to investigate similarities and difference in the microvascular architecture of the renal glomerulus of birds and mammals, we observed the microvasculature of the renal glomerulus of Chrysolophus pictus and the mouse using microvascular c...

Griffith, R. S.; Black, H. R., 1962: Comparison of antimicrobial activity of erythromycin estolate and demethylchlortetracycline against hemolytic streptococci. Propionyl erythromycin lauryl sulfate in a single dose of 125 mg produces higher serum antimicrobial activity against beta-hemolytic streptococci than does 150 mg of demethylchlortetracycline. The serum activity of the erythromycin preparation is...

Rao, Prakash.; Mohapatra, KK., 1993: Occurrence of the knot (Calidris canutus) in Andhra Pradesh. Journal of the Bombay Natural History Society. December; 903: 509