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Effect of 5 hydroxy tryptophan on electro cortical activity and breathing movements of fetal sheep



Effect of 5 hydroxy tryptophan on electro cortical activity and breathing movements of fetal sheep



American Journal of Obstetrics & Gynecology 141(3): 271-275



5-Hydroxytryptophan administered i.v. to sheep fetuses, in which chronic catheters were placed in the carotid artery, jugular vein and trachea and EEG electrodes in the brain, caused prolonged high-voltage electrocortical activity in all fetuses. In those more mature fetuses (> 126 days) there was also a significant increase in respiratory activity. The respiratory activity involved the diaphragmatic and intercostal muscle movement.

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Accession: 005214898

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PMID: 6974499



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