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Effect of fibrino lysin and heparin on kinetic properties of blood platelets and redox processes in patients with myo cardial infarction

, : Effect of fibrino lysin and heparin on kinetic properties of blood platelets and redox processes in patients with myo cardial infarction. Kardiologiya 18(1): 115-118

Complex study of blood platelet adhesion and aggregation, blood coagulation activity and redox processes was conducted in 340 patients with myocardial infarction, 53 of them before and after treatment with fibrinolysin and heparin. In patients with myocardial infarction, particularly in the 1st days of the disease and with the development of cardiogenic shock and pulmonary edema, the adhesion and aggregation of blood platelets increase with parallel increase in the content of incompletely oxidized products in the blood. A definite parallel was found between the changes in the kinetic properties of platelets and the redox processes. A decrease in the platelet kinetic properties and improvement in the redox processes due to the effect of fibrinolysin and heparin were observed.

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Related references

Panchenko V.M.; Dmitrieva Z.A.; Pastorova V.E., 1971: Effect of fibrino lysin with heparin and thrombolytin on the indices of hemo coagulation in patients with myo cardial infarction and thrombo embolic complications. Terapevticheskii Arkhiv 43(8): 95-99

Andreenko G.V.; Bessolitsyna L.A., 1977: Changes in the fibrinolysis system in patients with acute myo cardial infarction after intra coronary administration of fibrino lysin with heparin. Terapevticheskii Arkhiv 49(4): 8-13

Anshelevich Y.V.; Slaidyn A.K.; Sporan V.G., 1972: Effectiveness of treating myo cardial infarction with fibrino lysin and heparin. Latvijas Psr Zinatnu Akademijas Vestis (7): 117-120

Krasheninnikova N.G.; Zil Berman D.B.; Taikh Y.I.; Chechik E.A.; Kamenetskaya I.Y.; Matushenko E.A.; Yanovskii A.D.; Korkushko O.V.; Kozlova L.L., 1967: Efficiency of early use of fibrino lysin cardio vasc during acute myo cardial infarction in conditions of emergency aid heparin hematol human. Vrachebnoe Delo (2): 39-42

Mombelli G.; I.H.f V.; Haeberli A.; Straub P.W., 1983: Effect of heparin on plasma fibrino peptide a in acute myo cardial infarction. Thrombosis & Haemostasis 50(1): 96

Chazov E.I.; Matveeva L.S.; Mazaev A.V.; Sargin K.E.; Sadovskaya G.V.; Ruda M.Ya, 1976: Intra coronary administration of fibrino lysin in acute myo cardial infarction. Terapevticheskii Arkhiv 48(4): 8-19

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Romanovskaya V.K., 1968: Ruptures of the heart muscle in myo cardial infarctions and the role of anti coagulants human heparin hematol enz fibrino lysin. Vrachebnoe Delo (3): 31-35

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