EurekaMag
+ Translate
+ Most Popular
The pigeon tick (Argas reflexus): its biology, ecology, and epidemiological aspects
Prevalence of hemoglobin abnormalities in Kebili (Tunisian South)
Lipogranuloma: a preventable complication of dacryocystorhinostomy
Value of basal plasma cortisol assays in the assessment of pituitary-adrenal insufficiency
Bees from the Belgian Congo. The acraensis group of Anthophora
Placing gingival retraction cord
Total serum IgE, allergy skin testing, and the radioallergosorbent test for the diagnosis of allergy in asthmatic children
Acariens plumicoles Analgesoidea parasites des oiseaux du Maroc
Injuries of terminal phalanges of the fingers in children
Biology of flowering and nectar production in pear (Pyrus communis)
Das Reliktvorkommen der Aspisviper (Vipera aspis L.) im Schwarzwald
Hydrological modelling of drained blanket peatland
Pathologic morphology and clinical significance of the anomalous origin of the left circumflex coronary artery from the right coronary artery. General review and autopsy analysis of 30 cases
Cyto genetic analyses of lymphocyte cultures after exposure to calcium cyclamate
Axelrodia riesei, a new characoid fish from Upper Rio Meta in Colombia With remarks concerning the genus Axelrodia and description of a similar, sympatric, Hyphessobrycon-species
Favorable evolution of a case of tuberculosis of pancreas under antibiotic action
RIFM fragrance ingredient safety assessment, Valencene, CAS Registry Number 4630-07-3
Parenteral microemulsions: an overview
Temperate pasture: management for grazing and conservation
Evaluation of a new coprocessed compound based on lactose and maize starch for tablet formulation
Thermal expansion and cracking of three confined water-saturated igneous rocks to 800C
Revision of the genera of the tribe Stigmoderini (Coleoptera: Buprestidae) a discussion of phylogenetic relationships
Anal tuberculosis. Report of a case
Gastric tuberculosis in the past and present
Adaptive responses of the cardiovascular system to prolonged spaceflight conditions: assessment with Holter monitoring

Effect of gamma irradiation on disodium alpha-sulfobenzylpenicillin in solid state


Effect of gamma irradiation on disodium alpha-sulfobenzylpenicillin in solid state



International Journal of Applied Radiation and Isotopes 28(8): 723-726



ISSN/ISBN: 0020-708X

PMID: 892926

The effect of .gamma. irradiation on hydrated crystal of disodium .alpha.-sulfobenzylpenicillin (I) in solid state was studied in relation to the radiation sterilization. From the decomposition products, at least 2 processes can be recognized during .gamma. radiolysis of (I). One leads to C-SO3Na scission giving benzylpenicillin, and the 2nd to hydrolysis of the .beta.-lactam in (I), giving .alpha.-sulfobenzylpenicilloic acid. Radiation sterilization of (I) apparently is feasible.

Please choose payment method:






(PDF emailed within 1 workday: $29.90)

Accession: 005240729

Download citation: RISBibTeXText

Related references

Clinical aspects of di sodium alpha sulfobenzyl penicillin a new synthetic penicillin. Hejzlar, Miroslav, Miroslav Semonsky And Stanislav Masak (Ed ) Advances in Antimicrobial And Antineoplastic Chemotherapy Progress in Research And Clinical Application Vol I/1: Antimicrobial Chemotherapy 1 ; Vol I/2: Antimicrobial Chemotherapy 2 Proceedings Of The Viith International Congress Prague, Czechoslavakia, Aug 23-28, 1971 Xviii+677p (Vol I/1) Illus Map Xvii+772p (Vol I/2) Illus University Park Press: Baltimore, Md , U S A ; London, England 1005-1009, 1972

In vitro and in vivo anti bacterial activity of di sodium alpha sulfobenzyl penicillin a new semi synthetic penicillin. Hejzlar, Miroslav, Miroslav Semonsky And Stanislav Masak (Ed ) Advances in Antimicrobial And Antineoplastic Chemotherapy Progress in Research And Clinical Application Vol I/1: Antimicrobial Chemotherapy 1 ; Vol I/2: Antimicrobial Chemotherapy 2 Proceedings Of The Viith International Congress Prague, Czechoslavakia, Aug 23-28, 1971 Xviii+677p (Vol I/1) Illus Map Xvii+772p (Vol I/2) Illus University Park Press: Baltimore, Md , U S A ; London, England 1091-1093, 1972

Pharmacological studies of di sodium alpha sulfobenzyl penicillin sulfocillin. Journal Of Takeda Research Laboratories: 248-261, 1971

Studies of administration of di sodium alpha sulfobenzyl penicillin under surgical conditions of extracorporeal circulation. Shimane Journal of Medical Science 4(1): 56-60, 1980

Solid-state trapping of the hydroxyl radical formed by gamma-irradiation in ice and the scavenging effect of sodium L-ascorbate. Bioscience, Biotechnology, and Biochemistry 60: 71-5, 1996

Solid-state Spin Trapping of the Hydroxyl Radical Formed by Gamma-irradiation in Ice and the Scavenging Effect of Sodium l -Ascorbate. Bioscience, Biotechnology and Biochemistry 60(12): 1971-1975, 1996

Solid-state spin trapping of the hydroxyl radical formed by gamma-irradiation in ice and the scavenging effect of sodium L-ascorbate. Bioscience Biotechnology and Biochemistry 60(12): 1971-1975, 1996

Supplementary studies of intra muscular and intra peritoneal subacute toxicities of di sodium alpha sulfobenzyl penicillin sulbenicillin in rats. Journal of Takeda Research Laboratories 31(2): 221-237, 1972

Pharmaco kinetics of a new broad spectrum semi synthetic penicillin alpha sulfobenzyl penicillin sulbenicillin. Acta Pharmacologica et Toxicologica Suppl 35(1): 30, 1974

Blood penicillin levels in man following administration of alpha, beta-bis(N,N-dimethyl-p-sulfonamido-benzylamino-ethane dipenicillin G associated with sodium penicillin G, of 1-(p-chlorobenzyl)-2-pyrrolidinyl-methyl-benzimidazole penicillin G associated with sodium penicillin G and of procaine penicillin. Bollettino Dell'istituto Sieroterapico Milanese 38: 335-341, 1959

The effect of gamma-irradiation on amylose in solid state. Agric And Biol Chem 25(7): a-44, 1961

Effect of gamma irradiation on cefotaxime in the solid state. Radiation Physics and Chemistry 45(2): 223-229, 1995

Semi synthetic beta lactam antibiotics part 4 the x ray analysis of mono potassium alpha sulfophenyl acetate mono hydrate the configuration of the acyl side chain of alpha sulfobenzyl penicillin. Chemical and Pharmaceutical Bulletin (tokyo): 1037-1041, 1973

Therapeutic effect of sulfobenzyl-penicillin (SB-PC) on the concentration of SB-PC in human bile. Japanese Journal of Antibiotics 28(6): 778-784, 1975

Stability of cefuroxime following gamma-irradiation in the solid state. Radiation Physics and Chemistry 43(4): 343-348, 1994