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Effect of high dose of nicotinic acid on bile acid metabolism in rats fed cholesterol free and cholesterol containing diet



Effect of high dose of nicotinic acid on bile acid metabolism in rats fed cholesterol free and cholesterol containing diet



Indian Journal of Biochemistry & Biophysics 19(3): 228-229



Effects of administration of high dose of nicotinic acid on the concentration of aortic cholesterol and fecal excretion of neutral sterols and bile acids were studied in rats fed cholesterol-free and cholesterol-containing diets. High dose of nicotinic acid as compared to adequate dose caused significant decrease in aortic cholesterol and increase in the fecal excretion of neutral sterols and bile acids.

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Accession: 005243819

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PMID: 7173965



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