EurekaMag.com logo
+ Site Statistics
References:
53,214,146
Abstracts:
29,074,682
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Effect of miscleron clofibrate on di methyl hydrazine induced intestinal tumors in rats



Effect of miscleron clofibrate on di methyl hydrazine induced intestinal tumors in rats



Byulleten' Eksperimental'noi Biologii i Meditsiny 90(9): 350-352



Intestinal tumors were induced in male rats by dimethylhydrazine (14 mg/kg body weight s.c. once a week for 20 wk). Some of the animals received clofibrate per os [by mouth] in a dose of 25 mg a day, 5 times wk. Clofibrate did not influence the developmental frequency of the intestinal tumors, but significantly decreased the number of medium size and large tumors. The possible mechanisms of clofibrate action as well as the use of clofibrate and some related agents in oncology are discussed.

(PDF 0-2 workdays service: $29.90)

Accession: 005254451

Download citation: RISBibTeXText



Related references

Effect of miscleron clofibrate on induction of intestinal tumors by di methyl hydrazine in rats. Bulletin of Experimental Biology & Medicine 90(9): 1280-1282, 1980

Effect of miscleron (clofibrate) on induction of intestinal tumors by dimethylhydrazine in rats. Bulletin of Experimental Biology and Medicine 90(3): 1280-1282, 1980

Effect of miscleron clofibrate on the carcinogenic effect of 7 12 di methyl benz a anthracene and nitroso methyl urea in female rats. Voprosy Onkologii (St Petersburg) 27(3): 64-67, 1981

Diet liver function and di methyl hydrazine hydrazine induced gastro intestinal tumors in male wistar rats. British Journal of Cancer 39(6): 731-739, 1979

Intestinal tumors induced in rats with 1 2 di methyl hydrazine. Voprosy Onkologii (St Petersburg) 18(1): 64-71, 1972

Dose response sex differences and the effect of bran in di methyl hydrazine induced intestinal tumorigenesis in rats. Toxicology Letters (Shannon) 48(1 PART 2): A147, 1979

Dose response sex difference and the effect of bran in di methyl hydrazine induced intestinal tumorigenesis in rats. Toxicology & Applied Pharmacology 55(3): 417-422, 1980

Effect of age on the induction of intestinal tumors in mice by 1 2 di methyl hydrazine. Byulleten' Eksperimental'noi Biologii i Meditsiny 92(12): 705-707, 1981

1 2 di methyl hydrazine induced colonic tumors in rats. Biomedicine Express (Paris) 32(1): 41-45, 1980

2 di methyl hydrazine induced colonic tumors in rats. Biomedicine Express (paris): 41-45, 1980

2 di methyl hydrazine induced intestinal cancer in rats fed beef or soybean protein. Nutrition Reports International: 335-342, 1979

Pathological features of the colonic tumors induced in rats by the administration of 1 2 di methyl hydrazine. Virchows Archiv B Cell Pathology 29(3): 211-224, 1978

Effect of miskleron (clofibrate) on dimethylhydrazine induction of intestinal tumors in rats. Biulleten' Eksperimental'noi Biologii i Meditsiny 90(9): 350-352, 1980

Strain susceptibility and resistance to 1 2 di methyl hydrazine induced enteric tumors in germ free rats. Proceedings of the Society for Experimental Biology and Medicine 158(1): 89-91, 1978

Chemo therapeutic studies on n nitrosoacetoxymethyl methylamine induced and 1 2 di methyl hydrazine induced colonic tumors in rats mono therapy with 5 fluoro uracil ftorafur cgp 6809 and cgp 15720a. Journal of Cancer Research & Clinical Oncology 104(1-2): 115-132, 1982