EurekaMag.com logo
+ Site Statistics
References:
53,214,146
Abstracts:
29,074,682
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Effect of moderate exercise on urinary 3 methoxy 4 hydroxyphenyl glycol in depressed patients



Effect of moderate exercise on urinary 3 methoxy 4 hydroxyphenyl glycol in depressed patients



Pharmakopsychiatrie Neuro-Psychopharmakologie 12(5): 351-356



This study attempted to clarify sources of artifact in biochemical studies with affective disorders in which 3-methoxy-4-hydroxy phenylglycol (MHPG) is used as a measurement of change in CNS norepinephrine (NE) turnover. Substantial increases in urinary MHPG excretion occurred in 10 of the 11 patients when they increased their level of physical activity (0.5 .+-. .14 mg/12 h vs. 1.54 .+-. .49 mg/12 h). Increases were observed in NE (19.2 .+-. 5.1 .mu.g/12 h vs. 25.2 .+-. 3.7 .mu.g/12 h). In 4 patients in whome CSF MHPG levels were obtained, a consistent increase of MHPG levels was observed during the activity period. Elevation of these metabolites was not correlated with changes in depression as reflected by psychiatric observation and rating scales. A considerable amount of lability in urinary and CSF MHPG levels occurred during an unchanging affective state. Careful controls for activity and stress in psychiatric patients were suggested when urinary MHPG is used as an index of central NE turnover.

(PDF 0-2 workdays service: $29.90)

Accession: 005254579

Download citation: RISBibTeXText



Related references

4 methoxy 3 hydroxyphenyl glycol as an internal standard for the determination of 3 methoxy 4 hydroxyphenyl glycol in urine results obtained in depressed patients and healthy controls. Journal of Clinical Chemistry & Clinical Biochemistry 18(9): 579-584, 1980

Effect of diet on urinary 3 methoxy 4 hydroxyphenyl glycol excretion in depressed patients and normal control subjects. American Journal of Psychiatry 134(8): 914-916, 1977

Urinary 3 methoxy 4 hydroxyphenyl glycol in subgroups of depressed patients and normal controls. Neuropsychobiology 16(2): 91-100, 1980

Urinary 3 methoxy 4 hydroxyphenyl glycol and clinical response to amitriptyline in depressed patients. American Journal of Psychiatry 137(10): 1183-1187, 1980

The effect of lithium on urinary 3 methoxy 4 hydroxyphenyl glycol in uni polar and bi polar depressed patients. Psychopharmacologia 42(3): 277-282, 1975

Phenelzine in depressed patients effects on urinary 3 methoxy 4 hydroxyphenyl glycol excretion in relation to clinical response. Neuropsychobiology 3(1): 49-55, 1977

Effects of desipramine on diurnal rhythms of plasma 3 methoxy 4 hydroxyphenyl glycol in depressed patients. Psychopharmacology Bulletin 18(4): 221-223, 1982

Controlled exercise elevates plasma but not urinary 3 methoxy 4 hydroxyphenyl ethylene glycol and vanillyl mandelic acid. Psychiatry Research 4(1): 13-20, 1981

Lack of correlation between plasma 3 4 dihydroxyphenylethylene glycol and urinary 3 methoxy 4 hydroxyphenylethylene glycol levels in depressed patients. Biological Psychiatry 21(10): 900-906, 1986

Urinary 3 methoxy 4 hydroxyphenyl glycol and ward behavior in unmedicated psychiatric patients. Psychiatry Research 10(4): 275-284, 1983

Response to amitriptyline and urinary 3 methoxy 4 hydroxyphenyl glycol in bi polar depressive patients. Neuropsychobiology 5(4): 181-184, 1979

Effect of moderate exercise on urinary MHPG in depressed patients. Pharmakopsychiatrie, Neuro-Psychopharmakologie 12(5): 351-356, 1979

Urinary 3 methoxy 4 hydroxyphenyl glycol in anorexia nervosa patients with and without concomitant major depressive disorder. Journal of Psychiatric Research 18(2): 149-160, 1984

Growth hormone responsiveness to hypo glycemia and urinary 3 methoxy 4 hydroxyphenyl glycol in affective disease patients preliminary observations. Sachar, Edward J (Ed ) Hormones, Behavior, And Psychopathology 65th Annual Meeting March 1975 Xviii+307p Illus Raven Press Publishers: New York, N Y , U S A Isbn 0-89004-062-1 233-235, 1976