The effects of farmyard manure (FYM), poultry manure (PoM) and piggery manure (PiM) on the yield and nutrition of wheat (T. aestivum L. var. S-308) with varying rates of NPK fertilizers were studied. The treatments included 4 rates of NPK with 2 rates each of the 3 types of manure and 1 combined treatment of MgSZnCuMn. The grain and total dry matter yields were significantly increased by manures and by MgSZnCuMn at all rates of NPK. The beneficial effects of manures were mainly due to the better nutrition of the plants. Though the PoM had the highest contents of N and Ca only, it resulted in the highest uptake of all the nutrients. The low yields with FYM and PiM have resulted from the lower nutrient uptake, besides a significant decrease in Ca uptake. Ca has been suggested to be the element which determined the superiority of PoM and prevented the antagonistic effects of FYM on the uptake of Mg, Zn, Cu and Mn at higher rates of NPK.